Bmi-1 (F270)Rabbit pAb

Bmi-1 (F270)Rabbit pAb

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SKU
ELK-EA363
Catalog Number: ELK-EA363
Reactivity: Human
Applications: WB
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Background:
Bmi1 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit . Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16 INK4A and p19 ARF genes and is required for maintenance of adult hematopoietic and neural stem cells .

Cellular localization: Cytoplasm, Nucleus

Specificity: Human

Alternative Names:
PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51

Immunogen: Recombinant Protein

Isotype: Rabbit Polyclonal IgG

Concentration: 1mg/ml

Recommended dilutions: WB 1:1,000-2,000

Observed band: 37-43kDa

GeneID: 100532731

Swiss-Prot No.: P35226

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only
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