BMI1 (clone 3E3), anti-human
€0.00
In stock
SKU
BT-MCA2235
Catalog Number: BT-MCA2235
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): IHC, ICC, FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): IHC, ICC, FCM
Datasheet
Request Information
Background:
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Research Area: Epigenetics and nuclear signaling, Cancer, Cell biology, Stem cells
Synonyms: PCGF4, RNF51, MGC12685, FLVI2/BMI1
Immunogen: Purified recombinant fragment of human BMI1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Research Area: Epigenetics and nuclear signaling, Cancer, Cell biology, Stem cells
Synonyms: PCGF4, RNF51, MGC12685, FLVI2/BMI1
Immunogen: Purified recombinant fragment of human BMI1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
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