Bmi1 (clone ), anti-human, mouse, rat

Background:
The Bmi-1 was identified initially as an oncogene that cooperates with c-myc in the generation of B-cell lymphoma. It contributes to the maintenance of cell identity, stem cell self-renewal, cell cycle regulation, and oncogenesis by maintaining the silenced state of genes that promote cell lineage specification, cell death, and cell-cycle arrest.

Alternative Name:
BMI1, B lymphoma Mo MLV insertion region (mouse), B lymphoma Mo MLV insertion region 1 homolog, Bmi 1, BMI1, BMI1 polycomb ring finger oncogene, BMI1, Flvi 2/bmi 1, FLVI2/BMI1, MGC12685, Murine leukemia viral (bmi 1) oncogene homolog, Oncogene BMI 1, PCGF 4, PCGF4, Polycomb complex protein BMI 1, Polycomb complex protein BMI-1, Polycomb group protein Bmi1, Polycomb group ring finger 4, Polycomb group RING finger protein 4, RING finger protein 51, RNF 51, RNF51,

Application Dilution:
WB:1:1,000
IHC:1:200
ICC:1:200
FC:1:100-1:200

Specificity: Bmi1 monoclonal antibody detects endogenous levels of Bmi1 protein.

Immunogen:
Recombinant protein within human Bmi1 full sequence.

MW: 37kDa

Swiss-Prot: P35226(Human) P25916(Mouse)

Purification & Purity:
ProA affinity purified

Format:
Mouse IgG2a, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.