BMI1 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM1930b
Catalog Number: AC-AM1930b
Size: 80 µl, 400 µl
Isotype: mouse IgG1,k
Clone Name: 282CT3.7.6
Applications: IF, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1,k
Clone Name: 282CT3.7.6
Applications: IF, WB
Datasheet
Request Information
Background:
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Other Names:
Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1, PCGF4, RNF51
Target/Specificity:
This BMI1 monoclonal antibody is generated from mouse immunized with BMI1 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: BMI1
Gene ID: 100532731;648
Primary Accession: P35226
NCBI Accession: NP_001190991.1;NP_005171.4
Other Accession: NP_005171.4
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Other Names:
Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1, PCGF4, RNF51
Target/Specificity:
This BMI1 monoclonal antibody is generated from mouse immunized with BMI1 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: BMI1
Gene ID: 100532731;648
Primary Accession: P35226
NCBI Accession: NP_001190991.1;NP_005171.4
Other Accession: NP_005171.4
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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