Bmi1 polyclonal, anti-human, mouse, monkey
€362.00
In stock
SKU
200185
Protein Family: Transcription Factors, Ubiquitins
Pathway and Disease: Cancers, Folding, Sorting and Degradation, Transcription
Description:
Polycomb complex protein BMI-1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex that maintains the transcriptionally repressive state of many genes, including Hox genes throughout development. PcG PRC1 complex forms Polycomb bodies that act via chromatin remodeling and histone modification. BMI-1 cooperates with Myc oncogene to produce B-lymphomas.
Alternate Names: Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1, PCGF4, RNF51
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P35226, NP_005171
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Bmi1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Cancers, Folding, Sorting and Degradation, Transcription
Description:
Polycomb complex protein BMI-1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex that maintains the transcriptionally repressive state of many genes, including Hox genes throughout development. PcG PRC1 complex forms Polycomb bodies that act via chromatin remodeling and histone modification. BMI-1 cooperates with Myc oncogene to produce B-lymphomas.
Alternate Names: Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1, PCGF4, RNF51
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P35226, NP_005171
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Bmi1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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