BMI1 Polyclonal Antibody

Background:
BMI- 1 is one of polycomb group genes,which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody reacts with the 37kd BMI1 protein.

Research Area: Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells, Cancer

Synonyms:
B lymphoma Mo MLV insertion region (mouse), B lymphoma Mo MLV insertion region 1 homolog, Bmi 1, BMI1, BMI1 polycomb ring finger oncogene, BMI1, Flvi 2/bmi 1, FLVI2/BMI1, MGC12685, Murine leukemia viral (bmi 1) oncogene homolog, Oncogene BMI 1, PCGF 4, PCGF4, Polycomb complex protein BMI 1, Polycomb complex protein BMI-1, Polycomb group protein Bmi1, Polycomb group ring finger 4, Polycomb group RING finger protein 4, RING finger protein 51, RNF 51, RNF51

Immunogen: Recombinant Mouse Polycomb complex protein BMI-1 protein

Swissprot: P25916
Gene ID: 12151

Calculated MW: 36 kDa
Observed MW: 36 kDa

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Concentration: 0.18 mg/mL
Dilution: WB 1:500-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.