BMP-15 Polyclonal Antibody

Background:
bone morphogenetic protein 15(BMP15) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016],

Alternative Names:
BMP15, GDF9B, Bone morphogenetic protein 15, BMP-15, Growth/differentiation factor 9B, GDF-9B

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human BMP15. AA range:291-340

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 45

GeneID: BMP15

Storage: -20°C/1 year

NOTE: For Research Use Only