BMP-3 Polyclonal Antibody

Background:
bone morphogenetic protein 3(BMP3) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016],

Alternative Names:
BMP3, BMP3A, Bone morphogenetic protein 3, BMP-3, Bone morphogenetic protein 3A, BMP-3A, Osteogenin

Immunogen: The antiserum was produced against synthesized peptide derived from human BMP-3. AA range:257-306

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 53

GeneID: BMP3

Storage: -20°C/1 year

NOTE: For Research Use Only