BMP-4 polyclonal, anti-human, mouse, rat, rabbit, chicken antibody

Background:
BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented thro µghout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP-4 (also designated BMP-2B), s µggesting that BMP-4 may play a role in activation of the Smad pathway.

Other Names:
BMP4, BMP-4, BMP 4, bone morphogenetic protein 4, BMP2B, BMP2B1

Primary Accession: P12644

Other Accession: AAC72278

Gene Name: BMP4

Gene ID: 652

Concentration (mg/ml): 0.5 mg/ml