BMP-6 Polyclonal Antibody

Background:
bone morphogenetic protein 6(BMP6) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016],

Alternative Names:
BMP6, VGR, Bone morphogenetic protein 6, BMP-6, VG-1-related protein, VG-1-R, VGR-1

Immunogen: The antiserum was produced against synthesized peptide derived from human BMP-6. AA range:103-152

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 57

GeneID: BMP6

Storage: -20°C/1 year

NOTE: For Research Use Only