BMP-6 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016],function:Induces cartilage and bone formation.,online information:Bone morphogenetic protein 6 entry,similarity:Belongs to the TGF-beta family.,subunit:Interacts with SOSTDC1.,

Synonyms: BMP6, VGR, Bone morphogenetic protein 6, BMP-6, VG-1-related protein, VG-1-R, VGR-1

Gene Name: BMP6

Gene ID: 654

SwissProt ID: P22004

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.