BMP-8A rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],function:Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.,online information:Bone morphogenetic protein 8A entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,

Synonyms: BMP8A, Bone morphogenetic protein 8A, BMP-8A

Gene Name: BMP8A

Gene ID: 353500

SwissProt ID: Q7Z5Y6

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.