BMP-9 rabbit polyclonal, anti-human, mouse

Backgroud: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016],function:Could be involved in bone formation.,online information:GDF2 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,

Synonyms: Growth/differentiation factor 2 (GDF-2, Bone morphogenetic protein 9, BMP-9)

Gene Name: GDF2 BMP9

Gene ID: 2658

SwissProt ID: Q9UK05

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.