BMP2 polyclonal, anti-human, mouse, rat

Background:
BMP-2 belongs to the TGF-β superfamily of proteins. BMP-2 plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. It is involved also in cardiac cell differentiation and epithelial to mesenchymal transition. Implantation of BMP-2 in a collagen sponge induces new bone formation and can be used for the treatment of bony defects, delayed union, and non-union.

Alternative Name:
BMP-2, BMP-2A, BDA2, BMP-2, BMP-2A, Bmp2, BMP2, BMP2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A,

Application Dilution:
WB:1:1,000
ICC:1:200
IHC:1:200
FC:1:100-1:200

Specificity: BMP2 polyclonal antibody detects endogenous levels of BMP2 protein.

Immunogen:
Synthetic peptide (KLH-coupled) within human BMP2 N terminal.

MW: 75kDa

Swiss-Prot: P12643(Human) P21274(Mouse) P49001(Rat)

Purification & Purity:
Peptide affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.