BMP2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

Synonyms: BDA2, BMP2A

Cellular Location: Secreted

Immunogen:
Recombinant protein of human BMP2

Gene Symbol: BMP2

Gene ID: 650

Swiss prot: P12643

Calculated MW: 45kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-100, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.