Bmp3 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP1714a
Background:
The BMPs belong to the TGF-Beta superfamilyBMPs stimulate the production of bone matrix proteins and thereby alter stromal cell and osteoclast proliferation, a key step in bone marrow development. In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells. BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.
Other Names:
Bone morphogenetic protein 3, BMP-3, Bone morphogenetic protein 3A, BMP-3A, Osteogenin, BMP3, BMP3A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1714a was selected from the N-term region of human Bmp3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BMP3
Gene ID: 651
Primary Accession: P12645
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The BMPs belong to the TGF-Beta superfamilyBMPs stimulate the production of bone matrix proteins and thereby alter stromal cell and osteoclast proliferation, a key step in bone marrow development. In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells. BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.
Other Names:
Bone morphogenetic protein 3, BMP-3, Bone morphogenetic protein 3A, BMP-3A, Osteogenin, BMP3, BMP3A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1714a was selected from the N-term region of human Bmp3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BMP3
Gene ID: 651
Primary Accession: P12645
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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