BMP3 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.

Synonyms: BMP-3A

Cellular Location: Secreted

Immunogen:
Recombinant protein of human BMP3

Gene Symbol: BMP3

Gene ID: 651

Swiss prot: P12645

Calculated MW: 53kDa

Recommended dilution:
WB 1:500-2000, IHC 1:100-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.