BMP4 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM1872b
Catalog Number: AC-AM1872b
Size: 80 µl, 400 µl
Isotype: mouse IgM,K
Clone Name: 192CT7.2.6
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgM,K
Clone Name: 192CT7.2.6
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Other Names:
Bone morphogenetic protein 4, BMP-4, Bone morphogenetic protein 2B, BMP-2B, BMP4, BMP2B, DVR4
Target/Specificity:
This BMP4 monoclonal antibody is generated from mouse immunized with BMP4 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: BMP4 (HGNC:1071)
Gene ID: 652
Primary Accession: P12644
NCBI Accession: NP_001193.2;NP_570911.2;NP_570912.2
Other Accession: NP_570911.2;NP_001193.2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Other Names:
Bone morphogenetic protein 4, BMP-4, Bone morphogenetic protein 2B, BMP-2B, BMP4, BMP2B, DVR4
Target/Specificity:
This BMP4 monoclonal antibody is generated from mouse immunized with BMP4 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: BMP4 (HGNC:1071)
Gene ID: 652
Primary Accession: P12644
NCBI Accession: NP_001193.2;NP_570911.2;NP_570912.2
Other Accession: NP_570911.2;NP_001193.2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
| Is Featured? | No |
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