BMP4 Polyclonal Antibody

Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.

Research Area: Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells

Synonyms:
BMP4, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME

Immunogen: Recombinant fusion protein of human BMP4 (NP_570912.2).

Swissprot: P12644
Gene ID: 652

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.