BMP4 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Research Area: Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells

Synonyms:
zgc:100779, BMP 2B, BMP 4, BMP-2B, BMP-4, BMP2B, BMP2B1, BMP4, BMP4, Bone morphogenetic protein 2B, Bone morphogenetic protein 4, DVR4, MCOPS6, MGC100779, OFC11, zbmp-4, ZYME

Immunogen: Recombinant protein corresponding to Mouse BMP4.

Swissprot: P21275, Q06826

Calculated MW: 47 kDa
Observed MW: 47 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 3 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.