Bmp4 polyclonal (N-term), anti-human

Bmp4 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP1715a
Catalog Number: AC-AP1715a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01857
Applications: WB, IHC-P
Datasheet

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Background:
Bmp4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Other Names:
Bone morphogenetic protein 4, BMP-4, Bone morphogenetic protein 2B, BMP-2B, BMP4, BMP2B, DVR4

Target/Specificity:
This Bmp4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-34 amino acids from the N-terminal region of human Bmp4.

Antigen Region:
5-34

Antigen Type: Synthetic Peptide

Gene Name: BMP4 (HGNC:1071)
Gene ID: 652
Primary Accession: P12644
NCBI Accession: NP_001193.2;NP_570911.2;NP_570912.2
Other Accession: O46576; P21275; Q2KJH1; NP_001193
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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