BMP5 Polyclonal Antibody

Background:
Bone morphogenetic protein-5 (BMP5), is a member of the transforming growth factor-beta (TGF-beta) superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. BMP5 may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. BMP5 is differentially regulated in multiple human cancers.

Research Area: Cardiovascular, Signal Transduction, Stem Cells

Synonyms:
BMP 5, BMP-5, Bmp5, BMP5, Bone morphogenetic protein 5, MGC34244

Immunogen: Synthetic peptide of human BMP5

Swissprot: P22003
Gene Accession: NP066551

Calculated MW: 52 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.54 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.