BMP6 polyclonal, anti-human

Quantity: 100 µg

Background:
Bone morphogenetic protein 6 is a protein that in humans is encoded by the BMP6 gene. It is mapped to 6p24-p23. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Description:
Rabbit IgG polyclonal antibody for Bone morphogenetic protein 6 (BMP6) detection. Tested with WB, ELISA in Human.

Synonyms:
BMP-6 antibody, Bmp6 antibody, BMP6_HUMAN antibody, Bone morphogenetic protein 6 antibody, Bone Morphogenic Protein 6 antibody, Decapentaplegic vegetal related antibody, DVR6 antibody, HGNC:12686 antibody, TGFB related vegetal related growth factor antibody, Transforming growth factor beta antibody, Vegetal related (TGFB related) cytokine antibody, Vegetal related growth factor (TGFB related) antibody, Vg related sequence antibody, VG-1-R antibody, VG-1-related protein antibody, Vg1 related sequence antibody, VGR antibody, VGR-1 antibody, VGR1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human BMP6 (383-419aa QSRNRSTQSQDVARVSSASDYNSSELKTACRKHELYV), different from the related mouse sequence by six amino acids, and from the related rat sequence by three amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.