BMP6 Polyclonal Antibody

Background:
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Research Area: Cancer, Cell Biology, Signal Transduction, Stem Cells

Synonyms:
BMP-6, Bmp6, BMP6, Bone morphogenetic protein 6, Bone Morphogenic Protein 6, Decapentaplegic vegetal related, DVR6, HGNC:12686, TGFB related vegetal related growth factor, Transforming growth factor beta, Vegetal related (TGFB related) cytokine, Vegetal related growth factor (TGFB related), Vg related sequence, VG-1-R, VG-1-related protein, Vg1 related sequence, VGR, VGR-1, VGR1

Immunogen: Synthetic peptide of human BMP6

Swissprot: P22004
Gene Accession: NP_001709

Calculated MW: 57 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-7406/sc-27408/sc-27409/sc-30508