BMPR2 Picoband polyclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO10056
Catalog Number: AC-ABO10056
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB, E
Datasheet
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Size: 100 µg
Isotype: Rabbit IgG
Applications: WB, E
Datasheet
Request Information
Description: Rabbit IgG polyclonal antibody for BMPR2 detection. Tested with WB, Direct ELISA in Human;Mouse;Rat.
Protein Function:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
Other Names: Bone morphogenetic protein receptor type-2, BMP type-2 receptor, BMPR-2, 2.7.11.30, Bone morphogenetic protein receptor type II, BMP type II receptor, BMPR-II, BMPR2, PPH1
Subcellular Localization: Cell membrane.
Tissue Specificity: Highly expressed in heart and liver.
Gene ID: 659
Immunogen: E. coli-derived human BMPR2 recombinant protein (Position: R455-K512).
Calculated MW: 115201
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage: At -20˚C; for one year. After reconstitution, at 4˚C; for one month. It can also be aliquotted and stored frozen at -20˚C; for a longer time. Avoid repeated freezing and thawing.
Protein Function:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
Other Names: Bone morphogenetic protein receptor type-2, BMP type-2 receptor, BMPR-2, 2.7.11.30, Bone morphogenetic protein receptor type II, BMP type II receptor, BMPR-II, BMPR2, PPH1
Subcellular Localization: Cell membrane.
Tissue Specificity: Highly expressed in heart and liver.
Gene ID: 659
Immunogen: E. coli-derived human BMPR2 recombinant protein (Position: R455-K512).
Calculated MW: 115201
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage: At -20˚C; for one year. After reconstitution, at 4˚C; for one month. It can also be aliquotted and stored frozen at -20˚C; for a longer time. Avoid repeated freezing and thawing.
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