BMPR2 polyclonal (N-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP2006b
Catalog Number: AC-AP2006b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1806
Applications: WB, IHC-P, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1806
Applications: WB, IHC-P, FC
Datasheet
Request Information
Background:
BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in BMPR2 have been associated with primary pulmonary hypertension.
Other Names:
Bone morphogenetic protein receptor type-2, BMP type-2 receptor, BMPR-2, Bone morphogenetic protein receptor type II, BMP type II receptor, BMPR-II, BMPR2, PPH1
Target/Specificity:
This BMPR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27~56 amino acids from the N-terminal region of human BMPR2.
Antigen Region:
27-56
Antigen Type: Synthetic Peptide
Gene Name: BMPR2
Gene ID: 659
Primary Accession: Q13873
NCBI Accession: NP_001195.2
Other Accession: O35607
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in BMPR2 have been associated with primary pulmonary hypertension.
Other Names:
Bone morphogenetic protein receptor type-2, BMP type-2 receptor, BMPR-2, Bone morphogenetic protein receptor type II, BMP type II receptor, BMPR-II, BMPR2, PPH1
Target/Specificity:
This BMPR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27~56 amino acids from the N-terminal region of human BMPR2.
Antigen Region:
27-56
Antigen Type: Synthetic Peptide
Gene Name: BMPR2
Gene ID: 659
Primary Accession: Q13873
NCBI Accession: NP_001195.2
Other Accession: O35607
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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