BNIP3 Antibody (BH3 Domain Specific) Blocking peptide
€363.00
In stock
SKU
AC-BP1321a
Background:
NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
Other Names:
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1321a was selected from the region of human NIP3 BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BNIP3 (HGNC:1084)
Gene ID: 664
Primary Accession: Q12983
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
Other Names:
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1321a was selected from the region of human NIP3 BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BNIP3 (HGNC:1084)
Gene ID: 664
Primary Accession: Q12983
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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