BNIP3 polyclonal (BH3 Domain Specific), anti-human, mouse
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In stock
SKU
AC-AP1321a
Catalog Number: AC-AP1321a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3385
Applications: IHC-P, IF
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3385
Applications: IHC-P, IF
Datasheet
Request Information
Background:
NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
Other Names:
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3
Target/Specificity:
This BNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-252 amino acids from human BNIP3.
Antigen Region:
215-252
Antigen Type: Synthetic Peptide
Gene Name: BNIP3 (HGNC:1084)
Gene ID: 664
Primary Accession: Q12983
NCBI Accession: NP_004043.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
Other Names:
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3
Target/Specificity:
This BNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-252 amino acids from human BNIP3.
Antigen Region:
215-252
Antigen Type: Synthetic Peptide
Gene Name: BNIP3 (HGNC:1084)
Gene ID: 664
Primary Accession: Q12983
NCBI Accession: NP_004043.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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