BOD1 Polyclonal Antibody

Background:
Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis.Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.

Research Area: Cell biology, Epigenetics and Nuclear Signaling

Synonyms:
Biorientation defective 1, Biorientation defective protein 1, biorientation of chromosomes in cell division 1, Biorientation of chromosomes in cell division protein 1, BOD1, BOD1, FAM44B, family with sequence similarity 44, member B, Protein FAM44B

Immunogen: Synthetic peptide of human BOD1

Swissprot: Q96IK1
Gene Accession: NP_001153123

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.