Bone morphogenetic protein receptor type II, BMPR2 monoclonal, anti-human, mouse, rat
€0.00
In stock
SKU
BMA1047
Catalog Number: BMA1047
Size: 100 μg
Isotype: Mouse IgG
Reactivity: human, mouse, rat
Application(s): WB, IHC-P, ICC
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Size: 100 μg
Isotype: Mouse IgG
Reactivity: human, mouse, rat
Application(s): WB, IHC-P, ICC
Request Information
Background:
Bone morphogenetic protein receptor type II,BMPR2 is a serine/threonine receptor kinase. It bindsbone morphogenetic proteins, members of the TGF beta superfamily of ligands. BMPs are involved in a host of cellular functions including osteogenesis, cell growth and cell differentiation.Unlike the TGFβtype II receptor, which has a high affinity for TGF-β1, BMPR2 does not have a high affinity for BMP-2, BMP-7 and BMP-4, unless it is co-expressed with a type I BMP receptor.1The low affinity for ligands suggests that BMPR2 may differ in the from other type II TGF beta receptors in that the ligand may bind the type I receptor first.2
Immunogen:
Recombinant protein
Recommended Application:
Western Blot, WB(1:200-1:500); Immunohistochemistry, IHC-P (1:20-1:100); Immunocytochemistry, ICC (1:50-200)
Product Form: Liquid
Purification: Protein A purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
Bone morphogenetic protein receptor type II,BMPR2 is a serine/threonine receptor kinase. It bindsbone morphogenetic proteins, members of the TGF beta superfamily of ligands. BMPs are involved in a host of cellular functions including osteogenesis, cell growth and cell differentiation.Unlike the TGFβtype II receptor, which has a high affinity for TGF-β1, BMPR2 does not have a high affinity for BMP-2, BMP-7 and BMP-4, unless it is co-expressed with a type I BMP receptor.1The low affinity for ligands suggests that BMPR2 may differ in the from other type II TGF beta receptors in that the ligand may bind the type I receptor first.2
Immunogen:
Recombinant protein
Recommended Application:
Western Blot, WB(1:200-1:500); Immunohistochemistry, IHC-P (1:20-1:100); Immunocytochemistry, ICC (1:50-200)
Product Form: Liquid
Purification: Protein A purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
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