BPGM Polyclonal Antibody

Background:
2, 3-diphosphoglycerate (2, 3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2, 3-DPG synthesis via its synthetase activity, and 2, 3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms:
2, 2, 3-bisphosphoglycerate mutase, 2, 3-bisphosphoglycerate mutase, erythrocyte, 2, 3-bisphosphoglycerate synthase, 2, 3-diphosphoglycerate mutase, 3-bisphosphoglycerate mutase, 3-bisphosphoglycerate synthase, 3-diphosphoglycerate mutase, Ab2 098, AI323730, AL022789, Bisphosphoglycerate mutase, BPG dependent PGAM, BPG-dependent PGAM, Bpgm, C86192, DPGM, Erythrocyte 2, 3 bisphosphoglycerate mutase, erythrocyte, PMGE

Immunogen: Full length fusion protein

Swissprot: P07738
Gene Accession: BC017050

Calculated MW: 30 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.1 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.