BPI Polyclonal Antibody

Background:
This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

Research Area: Cardiovascular, Immunology, Microbiology

Synonyms:
Bactericidal permeability-increasing protein, Bactericidal/permeability increasing protein, BPI, BPI fold containing family D, member 1, BPI, BPIFD1, CAP 57, CAP57, rBPI, Recombinant BPI holoprotein, rBPI

Immunogen: Recombinant protein of human BPI

Swissprot: P17213
Gene Accession: BC040955

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-23292/sc-23293/sc-33131