BPNT1 antibody (clone 20), anti-human
€435.00
In stock
SKU
AC-AT1310a
Catalog Number: AC-AT1310a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT1310a">Request Information
Background:
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Other Names:
3'(2'),5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, PAP-inositol 1,4-phosphatase, PIP, BPNT1
Antigen Type:
Recombinant Protein
Gene Name: BPNT1
Gene ID: 10380
NCBI Accession: NP_006076.4
Primary Accession: O95861
Other Accession: NM_006085
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Other Names:
3'(2'),5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, PAP-inositol 1,4-phosphatase, PIP, BPNT1
Antigen Type:
Recombinant Protein
Gene Name: BPNT1
Gene ID: 10380
NCBI Accession: NP_006076.4
Primary Accession: O95861
Other Accession: NM_006085
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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