Bradykinin B1 R Polyclonal Antibody

Background:
bradykinin receptor B1(BDKRB1) Homo sapiens Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Alternative Names:
BDKRB1, BRADYB1, B1 bradykinin receptor, B1R, BK-1 receptor

Immunogen: The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 40

GeneID: BDKRB1

Storage: -20°C/1 year

NOTE: For Research Use Only