Bradykinin receptor B1 polyclonal, anti-human

Background:
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.

Other Names:
B1 bradykinin receptor, B1R, BK-1 receptor, BDKRB1, BRADYB1

Antigen Types:
Synthetic Peptide

Gene Name:
BDKRB1
Gene ID:
623
Primary Accession: P46663
Other Accession: NP_000701;623;