BRAF monoclonal, anti-human
€0.00
In stock
SKU
AC-AM1821a
Catalog Number: AC-AM1821a
Size: 80 µl, 400 µl
Isotype: mouse IgG1κ
Clone Name: 125CT13.3.5
Applications: WB, IF
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1κ
Clone Name: 125CT13.3.5
Applications: WB, IF
Datasheet
Request Information
Background:
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Other Names:
Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF, BRAF1, RAFB1
Target/Specificity:
This BRAF Monoclonal antibody is generated from mouse immunized with BRAF recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: BRAF (HGNC:1097)
Gene ID: 673
Primary Accession: P15056
NCBI Accession: NP_004324.2
Other Accession: NP_004324
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Other Names:
Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF, BRAF1, RAFB1
Target/Specificity:
This BRAF Monoclonal antibody is generated from mouse immunized with BRAF recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: BRAF (HGNC:1097)
Gene ID: 673
Primary Accession: P15056
NCBI Accession: NP_004324.2
Other Accession: NP_004324
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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