BRE Polyclonal Antibody

Background:
This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
BRE, BRCC4, BRCC45

Immunogen: Recombinant fusion protein of human BRE (NP_954661.1).

Swissprot: Q9NXR7
Gene ID: 9577

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.