BRK (PTK6) polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP7715a
Catalog Number: AC-AP7715a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3073/3074
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3073/3074
Applications: IHC-P, WB
Datasheet
Request Information
Background:
PTK6 is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation.
Other Names:
Protein-tyrosine kinase 6, Breast tumor kinase, Tyrosine-protein kinase BRK, PTK6, BRK
Target/Specificity:
This BRK (PTK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of human BRK (PTK6).
Antigen Region:
11-41
Antigen Type: Synthetic Peptide
Gene Name: PTK6
Gene ID: 5753
Primary Accession: Q13882
NCBI Accession: NP_001243287.1;NP_005966.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
PTK6 is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation.
Other Names:
Protein-tyrosine kinase 6, Breast tumor kinase, Tyrosine-protein kinase BRK, PTK6, BRK
Target/Specificity:
This BRK (PTK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of human BRK (PTK6).
Antigen Region:
11-41
Antigen Type: Synthetic Peptide
Gene Name: PTK6
Gene ID: 5753
Primary Accession: Q13882
NCBI Accession: NP_001243287.1;NP_005966.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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