BRMS-1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],function:May be a mediator of metastasis suppression in breast carcinoma.,similarity:Belongs to the BRMS1 family.,tissue specificity:Expression levels are higher in term placentas than in early placentas. Low levels of expression observed in normal pregnancies and in molar pregnancies.,

Synonyms: BRMS1, Breast cancer metastasis-suppressor 1

Gene Name: BRMS1

Gene ID: 25855

SwissProt ID: Q9HCU9

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.