BTK polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms: AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA

Cellular Location: Cell membrane Cytoplasm Nucleus Peripheral membrane protein

Immunogen:
Recombinant protein of human BTK

Gene Symbol: BTK

Gene ID: 695

Swiss prot: Q06187

Calculated MW: 76kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-100, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.