BTLA polyclonal, anti-human antibody

Background:
The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain. Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells. Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis

Other Names:
BTLA, CD272

Primary Accession: Q7Z6A9

Gene Name: BTLA {ECO:0000303|PubMed:12796776, ECO:0000312|HGNC:HGNC:21087}

Gene ID: 151888