BUB1 Polyclonal Antibody

Background:
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

Research Area: Cancer, Cell Biology

Synonyms:
Bub1, BUB1 budding uninhibited by benzimidazoles 1 homolog, BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast), BUB1 mitotic checkpoint serine/threonine kinase, BUB1, S. cerevisiae, homolog of, BUB1, BUB1A, BUB1L, Budding uninhibited by benzimidazoles 1 (yeast homolog), Budding uninhibited by benzimidazoles 1 homolog, Budding uninhibited by benzimidazoles 1, S. cerevisiae, homolog of, hBUB1, Homolog of mitotic checkpoint gene BUB1, Mitotic checkpoint gene BUB1, Mitotic checkpoint serine/threonine protein kinase BUB1, Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle checkpoint kinase, Putative serine/threonine protein kinase

Immunogen: Recombinant protein of human BUB1

Swissprot: O43683
Gene Accession: BC028201

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-18286/sc-31100/sc-31101/sc-28257