BUD31 Polyclonal Antibody

Background:
BUD31 (Protein G10 homolog, EDG-2) is a 144 amino acid protein encoded by the human gene BUD31. BUD31 is a nuclear protein that belongs to the BUD31 (G10) family. BUD31 is found on chromosome 7 which is about 158 milllion bases long, encodes over 1, 000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the long (q) arm of human chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
Bud31, BUD31 homolog (S. cerevisiae), BUD31, Cwc14, EDG 2, EDG2, fSAP17, Functional spliceosome associated protein 17, G10, G10 maternal transcript homolog, Maternal G10 transcript, Protein BUD31 homolog, Protein EDG-2, Protein G10 homolog, YCR063W

Immunogen: Full length fusion protein

Swissprot: P41223
Gene Accession: BC022821

Calculated MW: 17 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.7 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.