C/EBP α (phospho-S193) polyclonal, anti-mouse, rat
€328.00
In stock
SKU
BS64010
Background:
C/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP α is a basic region/leucine zipper transcription factor selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP α uses a bipartite structural motif to bind DNA and appears to function exclusively in terminally differentiated, growtharrested cells. In the liver, C/EBP α is a transactivator of several genes, which are regulated by growth hormone. Growth hormone enhances not only the levels of C/EBP α mRNA and protein, but also the DNA-binding activity of C/EBP α. C/EBP α functions as an important transcription factor that regulates different genes, including Prolactin gene expression.
Alternative Name:
CCAAT/enhancer-binding protein alpha, C/EBP alpha, CEBPA, C/EBP α, C/EBPα
Application Dilution: WB: 1:500~1:1000
Specificity: p-C/EBP α (S193) polyclonal antibody detects endogenous levels of C/EBP α protein only when phosphorylated at Ser193 (Mouse or Rat).
Immunogen:
Synthetic phosphopeptide derived from mouse C/EBP α around the phosphorylation site of Serine 193.
MW: ~ 37 kDa
Swis Prot.: P53566/P05554
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
C/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP α is a basic region/leucine zipper transcription factor selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP α uses a bipartite structural motif to bind DNA and appears to function exclusively in terminally differentiated, growtharrested cells. In the liver, C/EBP α is a transactivator of several genes, which are regulated by growth hormone. Growth hormone enhances not only the levels of C/EBP α mRNA and protein, but also the DNA-binding activity of C/EBP α. C/EBP α functions as an important transcription factor that regulates different genes, including Prolactin gene expression.
Alternative Name:
CCAAT/enhancer-binding protein alpha, C/EBP alpha, CEBPA, C/EBP α, C/EBPα
Application Dilution: WB: 1:500~1:1000
Specificity: p-C/EBP α (S193) polyclonal antibody detects endogenous levels of C/EBP α protein only when phosphorylated at Ser193 (Mouse or Rat).
Immunogen:
Synthetic phosphopeptide derived from mouse C/EBP α around the phosphorylation site of Serine 193.
MW: ~ 37 kDa
Swis Prot.: P53566/P05554
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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