c-Fos Polyclonal Antibody

Background:
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
FOS, AP-1, C-FOS, p55, c-Fos

Immunogen: Recombinant protein of human c-Fos

Swissprot: P01100
Gene ID: 2353

Calculated MW: 28 kDa/36 kDa/40 kDa
Observed MW: 60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.