c-fos polyclonal (C-term), anti-human
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In stock
SKU
AC-AP6585b
Catalog Number: AC-AP6585b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19537
Applications: WB, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19537
Applications: WB, FC
Datasheet
Request Information
Background:
The Fos family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These leucine zipper proteins can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Other Names:
Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, FOS, G0S7
Target/Specificity:
This c-fos antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-291 amino acids from the C-terminal region of human c-fos.
Antigen Region:
263-291
Antigen Type: Synthetic Peptide
Gene Name: FOS
Gene ID: 2353
Primary Accession: P01100
NCBI Accession: NP_005243.1
Other Accession: P12841; O77628
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
The Fos family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These leucine zipper proteins can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Other Names:
Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, FOS, G0S7
Target/Specificity:
This c-fos antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-291 amino acids from the C-terminal region of human c-fos.
Antigen Region:
263-291
Antigen Type: Synthetic Peptide
Gene Name: FOS
Gene ID: 2353
Primary Accession: P01100
NCBI Accession: NP_005243.1
Other Accession: P12841; O77628
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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