C-Kit/CD117(NT) polyclonal, anti- antibody
€275.00
In stock
SKU
AC-ABV11320-100
Catalog Number: AC-ABV11320-100
Size: 100 µl
Host: Rabbit IgG
Applications: WB, IHC, IF
Datasheet
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Size: 100 µl
Host: Rabbit IgG
Applications: WB, IHC, IF
Datasheet
Request Information
Background:
The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis, and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.
Other Names:
KIT, Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit
The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis, and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.
Other Names:
KIT, Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit
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