c-Met polyclonal, anti-human, mouse, rat, dog

Protein Family: Enzymes, Protein Kinases, Receptors and Channels

Pathway and Disease: Cancers, Cell Communication, Development and Behavior, Infectious Diseases, Signaling Molecules and Interaction

Description:
HGFR (MET), a tyrosine protein kinase, is the receptor for the hepatocyte growth factor and scater factor. Activation of HGFR after rearrangement with the TPR gene produces an oncogenic protein c-MET. Defects in HGFR/MET are a cause of hepatocellular carcinoma and renal carcinoma.

Alternate Names: Hepatocyte growth factor receptor, HGF receptor, Scatter factor receptor, SF receptor, HGF/SF receptor, Met proto-oncogene tyrosine kinase, c-Met

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P08581

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human c-Met.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.