c-Rel (phospho Ser503) Polyclonal Antibody

Background:
REL proto-oncogene, NF-kB subunit(REL) Homo sapiens This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014],

Alternative Names:
REL, Proto-oncogene c-Rel

Immunogen: The antiserum was produced against synthesized peptide derived from human Rel around the phosphorylation site of Ser503. AA range:470-519

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

GeneID: REL

Storage: -20°C/1 year

NOTE: For Research Use Only