c-SRC Polyclonal Antibody

Background:
SRC,also named as SRC1 and p60-Src,belongs to the protein kinase superfamily,Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation,migration,and transformation. In concert with PTK2B,SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
ASV, Avian sarcoma virus, c SRC, CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA, cSrc, EC 2.7.10.2, Neuronal CSRC tyrosine specific protein kinase, Neuronal SRC, Oncogene SRC, OTTHUMP00000174476, OTTHUMP00000174477, p60 Src, p60-Src, p60Src, pp60c src, pp60c-src, pp60csrc, Proto oncogene tyrosine protein kinase Src, Proto-oncogene c-Src, Proto-oncogene tyrosine-protein kinase Src, Protooncogene SRC, Protooncogene SRC Rous sarcoma, Src, SRC Oncogene, SRC proto oncogene non receptor tyrosine kinase, SRC, SRC1, Tyrosine kinase pp60c src, Tyrosine protein kinase SRC 1, Tyrosine protein kinase SRC1, v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog, V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian), v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian

Immunogen: Recombinant Human Proto-oncogene tyrosine-protein kinase Src protein

Swissprot: P12931

Calculated MW: 60 kDa
Observed MW: 60 kDa

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 1 mg/mL
Dilution: WB 1:1000-1:2000 IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.